Septic pelvic thrombophlebitis
Sepsis von Thrombophlebitis Sepsis: cause, symptoms, treatment options, types of, sepsis and diabetes
May 18, Author: Many cases present as benign, localized venous cords that resolve completely wie das Bein Ödem in den trophischen Geschwüren entfernen minimal intervention.
Some cases present as Sepsis von Thrombophlebitis systemic infections culminating in profound shock that is refractory to aggressive management, including operative intervention and intensive care.
See Presentation and Prognosis. A number of distinct clinical conditions have been identified, depending on the vessel involved, but all thrombophlebitides involve the same basic pathophysiology. Thrombosis and infection within a vein can occur throughout the body and can involve superficial or deep vessels. Notable examples are thrombophlebitis in the following see Etiology:. The approach to treatment of septic phlebitis depends on which structures are involved, the underlying etiology of the phlebitis, the causative organisms, and the patient's underlying physiology.
See Treatment and Medication. Peripheral septic thrombophlebitis is a common Sepsis von Thrombophlebitis that can develop spontaneously but more often is associated with breaks in the mit Krampfadern, wenn Sie ausführen können. Though most commonly caused by indwelling catheters, septic thrombophlebitis may also result from simple procedures such as venipuncture for phlebotomy and intravenous injection.
While infection must always be considered, catheter-related phlebitis can result from sterile chemical or mechanical irritation. Septic phlebitis of a superficial vein without frank purulence is known as simple phlebitis. Simple phlebitis is Sepsis von Thrombophlebitis benign, but when it is progressive, it can cause serious complications, and even death. Suppurative superficial thrombophlebitis is a more serious condition that can lead to sepsis and death, even with appropriate aggressive intervention.
Septic phlebitis of the deep venous system is a rare, but life-threatening, emergency that may fail to respond to even the most aggressive therapy. Any vessel can theoretically be involved, but the more common entities are detailed below.
Septic thrombophlebitis Sepsis von Thrombophlebitis the IVC or SVC is primarily the result of central venous catheter placement, with increased incidence in burn patients and those receiving total parenteral nutrition.
The mortality rate of these infections is high, Sepsis von Thrombophlebitis, but cases of successful treatment Krampfadern operieren been reported.
Lemierre syndrome is a suppurative thrombophlebitis of the internal jugular vein caused by oropharyngeal infections such as tonsillitis and dental infections.
Spread of the infection into the parapharyngeal space that houses the carotid sheath leads to local inflammation and thrombosis of the jugular vein, Sepsis von Thrombophlebitis.
Lemierre syndrome is easily missed and is more common than is generally appreciated. Less commonly, septic emboli may traverse a patent foramen ovale and cause distant metastatic infections such as septic arthritis, osteomyelitis, and hepatic abscesses.
Septic pelvic thrombophlebitis and ovarian vein thrombophlebitis are seen principally as a complication of puerperal uterine infections, such Sepsis von Thrombophlebitis endometritis and septic abortion. In abdominal infections, such as appendicitis and diverticulitis, infection may spread to cause neighboring septic phlebitides. Thrombophlebitis of the intracranial venous sinuses is a particularly serious problem and can involve the cavernous sinus, the lateral sinus, or the superior sagittal sinus.
Cavernous sinus thrombophlebitis is caused by infection of the medial third of the face known as the "danger zone," ethmoid and sphenoid sinusitis, and, occasionally, oral infections.
Mastoiditis and otitis media are rarely associated with septic phlebitis of the lateral sinuses, while thrombophlebitis of the superior sagittal Sepsis von Thrombophlebitis is the rarest and is primarily associated with meningitis. More than a third of cases of intracranial septic thrombophlebitis are fatal.
For patient education information, see Phlebitis. Placement of an intravascular catheter is the main causative factor in the development of phlebitis and septic thrombophlebitis. Infection can be introduced during the placement of the catheter or bacteria can colonize first the hub and then the lumen of the catheter before they gain access to the intravascular space. Causative organisms are diverse and include skin and subcutaneous tissue pathogens, enteric bacteria, and flora causing infection in the genitourinary Sepsis von Thrombophlebitis. The most common infective organism is Staphylococcus aureus, but coagulase-negative staphylococci, Sepsis von Thrombophlebitis, enteric gram-negative bacilli, and enterococci are also frequently implicated.
These infections are often polymicrobial. Septic pelvic and ovarian vein thrombophlebitides are often puerperal and typically occur within 3 weeks of delivery, Sepsis von Thrombophlebitis.
Damage to the intima of pelvic ileofemoral vessels during vaginal or cesarean delivery is thought to contribute to the process of thrombosis. Hypercoagulability secondary to pregnancy, as well as the venous stasis common in the peripartum Sepsis von Thrombophlebitis, also contribute. It may also be caused by other intra-abdominal infections drained by or contiguous with the portal vein.
Bacteroides fragilis is the most common pathogen, but other bacteria, such as Escherichia coliKlebsiella species, and other Bacteroides species, are also found. There has been a case report in which an IVC filter was found to be the nidus of a septic phlebitis. Candida albicans is the most common fungal pathogen, but cases have also been attributed to Candida glabrata. Like abdominal and pelvic thrombophlebitis, Lemierre syndrome is characterized by the migration of bacteria through the deep tissues.
In this infection, pathogens translocate through the pharynx or are drained from the pharynx into the lateral pharyngeal space, where they come near to the internal jugular vein. Inflammation, thrombosis, and infection may then ensue.
The predisposing infections that ultimately result in septic thrombosis of the dural venous sinuses are closely related to the venous anatomy of the face and head. Infections of the medial third of the face, Sepsis von Thrombophlebitis, involving the nose, periorbital regions, tonsils, and soft palate, have long been recognized risk factors, since these areas drain directly into the cavernous sinus via the facial veins, pterygoid plexus, and ophthalmic veins.
Infections of the sphenoid and ethmoid sinuses have been implicated, with bacteria spreading directly through the lateral wall or via emissary veins, Sepsis von Thrombophlebitis. While extremely rare, septic thrombophlebitis of the superior sagittal sinus is caused by bacterial meningitis, but frontal, ethmoid, and maxillary sinus infections and spread from infections in the lateral dural sinus have also been reported.
The microbiology of intracranial vascular infections depends in large part on the causative infective site. S aureus is by far the most common organism seen in cavernous sinus thrombosis and is responsible for all septic thromboses resulting from facial and sphenoid sinusitis.
Streptococci, anaerobes, and occasionally fungi are also seen in cavernous sinus thrombosis. Organisms responsible for superior sagittal sinus thromboses include those responsible for meningitis, notably S pneumoniae, while pathogens more representative of chronic otitis, such as ProteusS aureusE coliand anaerobes, were found to cause lateral sinus thrombophlebitis, Sepsis von Thrombophlebitis.
Catheter-associated bloodstream infection is a common problem well Sepsis von Thrombophlebitis by the hospital community, and major efforts have been made to combat this problem. Ina French study found that 9. Similar rates have been noted for central venous catheters. Given the rarity of pelvic, ovarian, jugular, portal, and dural vein septic thrombophlebitides, epidemiologic data describing their frequency are lacking, Sepsis von Thrombophlebitis.
In general, however, incidences of these deep vein infections appear to be rising, likely owing in part to the increased use of sophisticated diagnostic imaging. In an epidemiologic survey examining the frequency of septic pelvic thrombophlebitis, an overall incidence of 1: Lemierre syndrome is also infrequent but is easily missed and likely underdiagnosed. Reports from Europe suggested a rate of 0.
Extremes Sepsis von Thrombophlebitis age predispose patients to catheter-related septic thrombophlebitis. Vulnerability is also increased in elderly persons, likely secondary to concomitant illnesses and a nonspecific, age-related decline in immunologic function.
Garrison et al reported increased risk for the development of Sepsis von Thrombophlebitis complications from intravenous Sepsis von Thrombophlebitis placement in patients aged 50 years and older, Sepsis von Thrombophlebitis, with an odds ratio of 4.
Notable exceptions to the above age-related predispositions are Lemierre syndrome and septic pelvic and ovarian mit Krampfadern kann leben Lemierre disease occurs in healthy, Sepsis von Thrombophlebitis, young adults with a mean age of onset of 20 years, [ 7 ] while septic pelvic and ovarian thrombophlebitides occur in women of childbearing age.
Septic thrombophlebitis is a relatively rare disease that encompasses an array of clinical entities, so data on Sepsis von Thrombophlebitis rates are scarce, Sepsis von Thrombophlebitis.
Needless to say, it is a serious and dangerous disease, since the infection takes root in the central or peripheral venous system and can readily progress to sepsis and shock. Metastatic foci of infection are common, with septic pulmonary emboli, infective endocarditis, septic emboli to the central nervous system, osteomyelitis, septic arthritis, and even arteritis all adding to the morbidity and mortality burden Medizin für die Behandlung von Krampfadern this disease.
Serious complications in survivors include ocular palsies, hemiparesis, blindness, and pituitary insufficiency, Sepsis von Thrombophlebitis. Sepsis von Thrombophlebitis, however, pelvic and jugular thrombophlebitis appear to have become less deadly Sepsis von Thrombophlebitis the years.
Clinical Sepsis von Thrombophlebitis guidelines for the diagnosis and management of intravascular catheter-related infection: Thrombophlebitis in the elderly. Diagnosis and treatment of cannula-related intravenous sepsis in burn patients.
Candida septic thrombosis of the great central veins associated with central catheters. Clinical features and management. Central venous septic thrombophlebitis--the role of medical therapy. The evolution of Lemierre syndrome: Infect Dis Obstet Gynecol. Septic thrombosis of the dural venous sinuses.
Khardori N, Yassien M. Biofilms in device-related infections. Consequences of intravascular catheter sepsis. Puerperal septic pelvic thrombophlebitis: Am J Obstet Gynecol. Septic thrombophlebitis of the portal vein pylephlebitis: Candida inferior vena cava filter infection and septic thrombophlebitis. A year-old man with fever and abdominal pain after recent peritonsillar abscess drainage. Am J Emerg Med. Cavernous sinus thrombosis complicating sinusitis. Pediatr Crit Care Med. Bilateral cavernous sinus thromboses and intraorbital abscesses secondary to Streptococcus milleri.
Prospective multicenter study of Sepsis von Thrombophlebitis complications and risk factors for positive central-catheter cultures in intensive care unit patients. The risk of bloodstream infection in adults with different intravascular devices: Incidence and clinical epidemiology of necrobacillosis, including Lemierre's syndrome, in Denmark Riordan T, Wilson M. Cooley K, Grady S. Minimizing catheter-related bloodstream infections: Guidelines for the diagnosis, treatment and prevention Sepsis von Thrombophlebitis postoperative infections.
Sepsis von Thrombophlebitis Thrombophlebitis: cause, symptoms, treatment options, prevention
Septic pelvic thrombophlebitis was first described in Sepsis von Thrombophlebitis late s by Von Recklinghausen [ 1 ]. He proposed surgical excision as the treatment of choice, although subsequently Trendelenburg described successful management with pelvic vein ligation, Sepsis von Thrombophlebitis.
Medical therapy has since become the preferred treatment approach. There are two types of septic pelvic thrombophlebitis SPT: These two entities share common pathogenic mechanisms and often occur together, Sepsis von Thrombophlebitis, but they may differ in their clinical presentations Sepsis von Thrombophlebitis diagnostic findings. Patients with OVT usually present with fever and abdominal pain within one week after delivery or surgery, and thrombosis of the right ovarian Krampfadern Preise is visualized radiographically in about 20 percent of cases.
Patients with DSPT usually present within a few days after delivery or surgery with fever that persists despite antibiotics, Sepsis von Thrombophlebitis, in the absence of radiographic evidence of thrombosis. The physiologic conditions in the setting of septic pelvic thrombophlebitis fulfill Virchow's triad for the pathogenesis of thrombosis ie, endothelial damage, venous stasis, and hypercoagulability see "Overview of the causes of venous thrombosis":.
The pathophysiology of SPT was first described in the s in a series of reports describing a cohort of 70 women with fever following obstetric or gynecologic procedures [ ]. In each case, the diagnosis of SPT was confirmed by exploratory laparotomy, which demonstrated grossly palpable intravenous thrombi and seropurulent fluid. Histopathologic evaluation showed perivascular and intimal inflammatory exudate and frequent microabscesses but rare bacteria. Subscribers log in here.
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Resident, Fellow or Student. Literature review current through: This topic last updated: Sepsis von Thrombophlebitis content on the UpToDate website is not intended nor recommended as a substitute for medical advice, diagnosis, or treatment. Always seek the advice of your own physician or other qualified health care professional regarding any medical questions or conditions.
UpToDate is the most trusted clinical decision support resource in the world. Learn how UpToDate can help you. Deep vein thrombosis in pregnancy: Epidemiology, pathogenesis, and diagnosis Factor V Leiden and activated protein C resistance Overview of the causes of venous thrombosis.
Endovascular infection Pelvic thrombophlebitis Postpartum fever Suppurative thrombophlebitis Thrombophlebitis Anticoagulation Cesarean section Endometritis Postpartum endometritis Pregnancy Vaginal delivery.
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Mar 15, · These cases highlight the risk factors that may be associated to the development of septic pelvic thrombophlebitis, von Recklinhausen Surviving Sepsis.
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Septic pelvic thrombophlebitis von Recklinhausen described this entity characterized by thrombosis of one or both ovarian When puerperal sepsis is.
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Mar 15, · These cases highlight the risk factors that may be associated to the development of septic pelvic thrombophlebitis, von Recklinhausen Surviving Sepsis.
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Thrombophilia (sometimes Platelet aggregation may be increased, and there are higher levels of coagulation proteins such as von Willebrand factor, fibrinogen.
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Septic pelvic thrombophlebitis was first described in the late s by Von Recklinghausen. He proposed surgical excision as the treatment of choice, although.